Development

IsoDDE doubles AlphaFold 3 on protein-ligand prediction

development2026-02-11

Claim

Isomorphic Labs unveiled IsoDDE, doubling AlphaFold 3's accuracy on protein-ligand prediction and identifying binding pockets from amino acid sequence alone.

Reporting date: 2026-02-11 (not necessarily the event date)

Sources

Attribution and reporting linked by this record; links do not imply independent verification.

Welcome to February 11, 2026 (theinnermostloop.substack.com)

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About

IsoDDE

Reported in

Welcome to February 11, 2026

Actor

Isomorphic Labs

Evidence for

Supersedes

AlphaGenome predicts expression from raw DNA

Referenced by

Welcome to February 11, 2026

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Citation formatCitation text

IsoDDE doubles AlphaFold 3 on protein-ligand prediction
Innermost Loop KB — secondary record
Reporting date: 2026-02-11
KB permalink: https://nicholsn.github.io/innermost-loop-kb/developments/2026-02-11-isodde-doubles-alphafold
Claim: Isomorphic Labs unveiled IsoDDE, doubling AlphaFold 3's accuracy on protein-ligand prediction and identifying binding pockets from amino acid sequence alone.
Attributed sources:
- Welcome to February 11, 2026 — https://theinnermostloop.substack.com/p/welcome-to-february-11-2026
This citation does not imply independent verification of linked-source claims.

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