Development

Weight-loss drugs work better on alternate weeks

development2026-03-04

Claim

A peer-reviewed case series found patients who plateau on weekly GLP-1 dosing maintain 17.2% weight loss and shed a further 2.3% on every-other-week dosing, with BMI falling from 30.0 to 24.6.

Reported metric: 17.2% + 2.3%

Reporting date: 2026-03-04 (not necessarily the event date)

Sources

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Welcome to March 4, 2026 (theinnermostloop.substack.com)

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Welcome to March 4, 2026

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Supersedes

A dual-cell therapy cures type 1 diabetes without lifelong drugs

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Weight-loss drugs work better on alternate weeks
Innermost Loop KB — secondary record
Reporting date: 2026-03-04
KB permalink: https://nicholsn.github.io/innermost-loop-kb/developments/2026-03-04-glp1-works-better-tapered
Claim: A peer-reviewed case series found patients who plateau on weekly GLP-1 dosing maintain 17.2% weight loss and shed a further 2.3% on every-other-week dosing, with BMI falling from 30.0 to 24.6.
Attributed sources:
- Welcome to March 4, 2026 — https://theinnermostloop.substack.com/p/welcome-to-march-4-2026
This citation does not imply independent verification of linked-source claims.

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