Issue

Welcome to June 8, 2026

issue

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The issue opens on longevity escape velocity — the point where medicine buys back more than a year of life expectancy for every year that passes. A UC San Diego team reports semaglutide slowing biological aging by 9% on the DunedinPACE clock, the first randomized placebo-controlled sign a GLP-1 drug touches aging itself.

The pattern is drugs built for something else: semaglutide for diabetes, colchicine for gout, a shingles vaccine now slowing cognitive decline.

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