Nolan Nichols
Informatics Leader · Biotech Data · Knowledge Graphs
I design and scale biomedical data platforms that help ambitious science programs move faster, integrate deeper, and deliver real impact.
Featured work
COMPASS — Target Discovery & Validation Platform
A data platform at Maze Therapeutics for target discovery and validation, translating human genetics into precision medicines.
Bridge Analytics Environment (BAE)
A shared data and analysis platform supporting open, collaborative research across central-nervous-system conditions.
LOKF — Linked Open Knowledge Format
A semantic profile of Google's Open Knowledge Format that turns a directory of markdown files into a queryable knowledge graph. This website is its reference implementation.
National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA)
A multi-site longitudinal study of adolescent brain development and substance use, for which I built the data-integration and informatics framework.
Neuroimaging Data Model (NIDM)
An open data-exchange standard that uses semantic-web technology to describe and share neuroimaging data, analysis provenance, and statistical results.
Recent writing
- Maze's COMPASS Platform: A Data Fabric for Drug Discovery and Development October 26, 2022
- Deploying Maze's COMPASS Platform on AWS September 15, 2021
- Focus on the Evidence: A Knowledge Graph Approach to Profiling Drug Targets October 15, 2020